This meaning refers to a knitted or woven item of clothing covering the foot and sometimes the lower leg.
I cannot find my other sock.
She wore thick wool socks.
This informal meaning refers to delivering a strong punch or blow.
He threatened to sock the attacker.
The boxer socked him in the jaw.
This less common informal use refers to a strong physical or emotional impact.
The drink has quite a sock to it.
The final scene delivers an emotional sock.